Single ricin detection by atomic force microscopy chemomechanical mapping
نویسندگان
چکیده
The authors report on a study of detecting ricin molecules immobilized on chemically modified Au 111 surface by chemomechanically mapping the molecular interactions with a chemically modified atomic force microscopy AFM tip. AFM images resolved the different fold-up conformations of single ricin molecule as well as their intramolecule structure of Aand B-chains. AFM force spectroscopy study of the interaction indicates that the unbinding force has a linear relation with the logarithmic force loading rate, which agrees well with calculations using one-barrier bond dissociation model. © 2009 American Institute of Physics. DOI: 10.1063/1.3190197
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تاریخ انتشار 2009